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    Emerg Infect Dis. 2008 Feb;14(2):320-2.

    Plasmodium falciparum malaria and atovaquone-proguanil treatment failure.

    Durand R, Prendki V, Cailhol J, Hubert V, Ralaimazava P, Massias L, Bouchaud O, Le Bras J.

    Hôpital Avicenne, Bobigny, France. remy.durand@avc.aphp.fr

    We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum-infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened.

    PMID: 18258131 [PubMed - indexed for MEDLINE]

    PMCID: PMC2600204

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    • Source: AHFS Consumer Medication Information

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