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The University of Connecticut, Department of Allied Health Sciences, Storrs, Connecticut 06269-2101, USA. matthew.j.wright@uconn.edu
Proton pump inhibitors (PPIs) are commonly used drugs, several of which are available without a prescription. Two recent studies have demonstrated increased hip fracture rates associated with PPI use. Theoretically, PPIs could impair intestinal calcium absorption resulting in increased rates of bone loss and a greater risk of fragility fracture.
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