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Curr Opin Chem Biol. 2008 Apr;12(2):134-40. doi: 10.1016/j.cbpa.2007.12.007. Epub 2008 Feb 20.

Non-heme iron-dependent dioxygenases: unravelling catalytic mechanisms for complex enzymatic oxidations.

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  • 1Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK. T.D.Bugg@warwick.ac.uk

Abstract

The article reviews recent developments in the study of the reaction mechanisms of non-heme iron-dependent dioxygenase enzymes, especially the catechol dioxygenases and arene (Rieske) dioxygenases.

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