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J Cataract Refract Surg. 2008 Feb;34(2):334-6. doi: 10.1016/j.jcrs.2007.09.020.

Intraocular lens staining associated with Prosed/DS.

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  • 1Commonwealth Eye Surgery, Lexington, Kentucky 40504, USA.


A 59-year-old pseudophakic woman with a history of Prosed/DS use demonstrated a discolored Tecnis Z9001 (AMO) silicone intraocular lens (IOL). Polymethyl methacrylate (PMMA), hydrophobic acrylic, silicone, and Collamer IOLs were submerged in a physiologic concentration of methylene blue at 35 degrees C for 8 weeks and evaluated. No staining was noted in PMMA or hydrophobic acrylic IOLs, variable staining was noted in silicone IOLs, and intense staining was noted in Collamer IOLs. This is the first report of IOL staining with systemic use of methylene blue and of Collamer lens staining characteristics.

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