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    Am J Infect Control. 2008 Feb;36(1):70-3.

    Fluoroquinolone resistance in pediatric bloodstream infections because of Escherichia coli and Klebsiella species.

    Kim JY, Lautenbach E, Chu J, Goyal M, Nachamkin I, McGowan K, Coffin S, Zaoutis T.

    Division of Infectious Diseases, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. kimj@email.chop.edu

    In pediatric bloodstream infections with fluoroquinolone (FQ)-resistant Escherichia coli and Klebsielia species, we noted an association between FQ resistance and extended-spectrum beta-lactamase (ESBL) production (OR, 12; 95% CI: 2.28-83.8). A case control study revealed no significant risk factors (including prior antibiotic use) for FQ resistance among ESBL E coli and Klebsiella species (ESBL-EK).

    PMID: 18241740 [PubMed - indexed for MEDLINE]

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