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1: Retrovirology. 2008 Feb 1;5:17.Click here to read Click here to read Links

RNA interference: a multifaceted innate antiviral defense.

The RNA interference mechanism utilizes short RNA duplexes to either suppress or induce target gene expression. Post-transcriptional regulation mediated by microRNA is an integral component of innate antiviral defense. The magnitude and the efficiency of viral restriction guided by RNA-based defenses, as well as the full physiological implication of host-pathogen engagement, constitute exciting areas of investigation in the biology of non-coding RNAs.

PMID: 18241347 [PubMed - indexed for MEDLINE]

PMCID: PMC2259359