Bull World Health Organ. 1975;52(4-6):517-21.

Pathogenesis of Machupo virus infection in primates.

Abstract

Experimental Machupo virus infection of rhesus and cynomolgus monkeys produced a severe illness consisting of an initial clinical phase and a later neurological phase. Cumulative mortality during the two phases was 80% and 95% respectively. Attempts to alter the pathogenesis with decomplementation or immunosuppression resulted in earlier deaths of the monkeys.

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PMCID:: PMC2366670

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Cited by 4 PubMed Central articles

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