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Eur Respir J. 2008 Feb;31(2):416-69. doi: 10.1183/09031936.00099306.

Outcomes for COPD pharmacological trials: from lung function to biomarkers.

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  • 1Unit of Respiratory Diseases, Dept of Internal Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy. mario.cazzola@uniroma2.it

Abstract

The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.

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PMID:
18238951
[PubMed - indexed for MEDLINE]
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