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[The presence of an ovarian granulocytic sarcoma concurrent with a type M2 acute myeloblastic leukemia: a case].

[Article in French]

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  • 1Service de Gynécologie-Obstétrique B, CHR Orléans.


The authors report a case of granulosa cell tumor principally located in the ovary associated with M2 type acute myeloblastic leukemia (AML) in a trisomy 22 patients. Surgery and chemotherapy were combined with a bone marrow allograft. Frequency of granulosa cell tumor is 8 percent or less of AML cases. Diagnosis is particularly difficult when haematologic expression occurs late in the disease course. An immunohistochemical work-up is required in these cases. Aetiopathogenesis is discussed. Treatment relies essentially on chemotherapy. The prognostic is variable according to different case reports in the literature.

[PubMed - indexed for MEDLINE]
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