Blood. 2008 Jun 15;111(12):5446-56. doi: 10.1182/blood-2007-06-093906. Epub 2008 Jan 23.

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines.

Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Döhner H, Hillmen P, Keating MJ, Montserrat E, Rai KR, Kipps TJ; International Workshop on Chronic Lymphocytic Leukemia.

Collaborators (11)

Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Döhner H, Hillmen P, Keating MJ, Montserrat E, Rai KR, Kipps TJ.

Source

Klinik I für Innere Medizin, Universität zu Köln, Köln, Germany. michael.hallek@uni-koeln.de

Erratum in

Blood. 2008 Dec 15;112(13):5259.

Abstract

Standardized criteria for diagnosis and response assessment are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies. Therefore, a National Cancer Institute-sponsored Working Group (NCI-WG) on chronic lymphocytic leukemia (CLL) published guidelines for the design and conduct of clinical trials for patients with CLL in 1988, which were updated in 1996. During the past decade, considerable progress has been achieved in defining new prognostic markers, diagnostic parameters, and treatment options. This prompted the International Workshop on Chronic Lymphocytic Leukemia (IWCLL) to provide updated recommendations for the management of CLL in clinical trials and general practice.

Comment in

Clearly defined response criteria evaluating treatment of CLL patients in clinical research trials. [Blood. 2010]
Clearly defined response criteria evaluating treatment of CLL patients in clinical research trials.Foon KA. Blood. 2010 Sep 9; 116(10):1817; author reply 1817-8.
Lymphocytes, B lymphocytes, and clonal CLL cells: observations on the impact of the new diagnostic criteria in the 2008 Guidelines for Chronic Lymphocytic Leukemia (CLL). [Blood. 2009]
Lymphocytes, B lymphocytes, and clonal CLL cells: observations on the impact of the new diagnostic criteria in the 2008 Guidelines for Chronic Lymphocytic Leukemia (CLL).Mulligan CS, Thomas ME, Mulligan SP. Blood. 2009 Jun 18; 113(25):6496-7; author reply 6497-8.
The proposed diagnostic criteria change for chronic lymphocytic leukemia: unintended consequences? [Blood. 2009]
The proposed diagnostic criteria change for chronic lymphocytic leukemia: unintended consequences?Hanson CA, Kurtin PJ, Dogan A. Blood. 2009 Jun 18; 113(25):6495-6.

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PMCID:: PMC2972576

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Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a re...
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines.
Blood. 2008 Jun 15 ;111(12):5446-56. doi: 10.1182/blood-2007-06-093906. Epub 2008 Jan 23 .

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