Emerg Infect Dis. 2007 Jul;13(7):1074-6. doi: 10.3201/eid1307.061538.

Little evidence for genetic susceptibility to influenza A (H5N1) from family clustering data.

Pitzer VE, Olsen SJ, Bergstrom CT, Dowell SF, Lipsitch M.

Source

Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA. vpitzer@hsph.harvard.edu

Abstract

The apparent clustering of human cases of influenza A (H5N1) among blood relatives has been considered as evidence of genetic variation in susceptibility. We show that, by chance alone, a high proportion of clusters are expected to be limited to blood relatives when infection is a rare event.

PMID:: 18214184; [PubMed - indexed for MEDLINE]
PMCID:: PMC2878232

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T32 AI07535/AI/NIAID NIH HHS/United States

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Little evidence for genetic susceptibility to influenza A (H5N1) from family clu...
Little evidence for genetic susceptibility to influenza A (H5N1) from family clustering data.
Emerg Infect Dis. 2007 Jul ;13(7):1074-6. doi: 10.3201/eid1307.061538.

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