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Emerg Infect Dis. 2007 Jul;13(7):1074-6. doi: 10.3201/eid1307.061538.

Little evidence for genetic susceptibility to influenza A (H5N1) from family clustering data.

Author information

  • 1Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA. vpitzer@hsph.harvard.edu

Abstract

The apparent clustering of human cases of influenza A (H5N1) among blood relatives has been considered as evidence of genetic variation in susceptibility. We show that, by chance alone, a high proportion of clusters are expected to be limited to blood relatives when infection is a rare event.

PMID:
18214184
[PubMed - indexed for MEDLINE]
PMCID:
PMC2878232
Free PMC Article

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