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Biochim Biophys Acta. 2008 Mar;1778(3):562-71. doi: 10.1016/j.bbamem.2007.12.015. Epub 2008 Jan 14.

Molecular components of the adherens junction.

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  • 1Center for Molecular Medicine, University of Cologne, LFI, 05, Room 59, Joseph Stelzmannstrasse 9, D-50931 Cologne, Germany.


Adherens junctions serve to couple individual cells into various arrangements required for tissue structure and function. The central structural components of adherens junctions are transmembrane adhesion receptors, and their associated actin-binding/regulatory proteins. The molecular machineries that organize these adhesion receptor complexes into higher order junction structures, and the functional consequences of this junctional organization will be discussed.

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