Anasthesiol Intensivmed Notfallmed Schmerzther. 2008 Jan;43(1):66-70; quiz 71.

[Optimization of hepatosplanchnic oxygenation in septic shock].

[Article in German]

Source

Klinik für Anästhesiologie des Universitätsklinikums Düsseldorf. christopher.beck@med.uni-duesseldorf.de

Abstract

Microcirculatory dysfunction, reduced oxygen supply and thus impaired hepatosplanchnic organ function, play a pivotal role in the clinical manifestation of sepsis and septic shock. Early correction of the perfusion mismatch is essential to maintain end-organ and gut mu-cosa barrier function and thus to prevent bacterial translocation, bacteraemia and possible multiple organ failure. This review will outline the clinical tightrope-walk optimizing hepa-tosplanchnic oxygen supply while maintaining adequate end-organ perfusion pressure and highlight the diagnostic challenges and limitations faced in clinical practice.

PMID:: 18196494; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Oxygen

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

OXYGEN - HSDB

Supplemental Content

Save items

Related citations in PubMed

Review Clinical review: influence of vasoactive and other therapies on intestinal and hepatic circulations in patients with septic shock. [Crit Care. 2004]
Review Clinical review: influence of vasoactive and other therapies on intestinal and hepatic circulations in patients with septic shock.
Asfar P, De Backer D, Meier-Hellmann A, Radermacher P, Sakka SG. Crit Care. 2004 Jun; 8(3):170-9. Epub 2003 Dec 29.
Effect of increased cardiac output on hepatic and intestinal microcirculatory blood flow, oxygenation, and metabolism in hyperdynamic murine septic shock. [Crit Care Med. 2005]
Effect of increased cardiac output on hepatic and intestinal microcirculatory blood flow, oxygenation, and metabolism in hyperdynamic murine septic shock.
Albuszies G, Radermacher P, Vogt J, Wachter U, Weber S, Schoaff M, Georgieff M, Barth E. Crit Care Med. 2005 Oct; 33(10):2332-8.
Review Effects of catecholamines on regional perfusion and oxygenation in critically ill patients. [Acta Anaesthesiol Scand Suppl....]
Review Effects of catecholamines on regional perfusion and oxygenation in critically ill patients.
Meier-Hellmann A, Reinhart K. Acta Anaesthesiol Scand Suppl. 1995; 107:239-48.
Review Splanchnic perfusion and sepsis. [Prog Clin Biol Res. 1989]
Review Splanchnic perfusion and sepsis.
Fry DE. Prog Clin Biol Res. 1989; 299:9-17.
Review Liver perfusion in sepsis, septic shock, and multiorgan failure. [Anat Rec (Hoboken). 2008]
Review Liver perfusion in sepsis, septic shock, and multiorgan failure.
Spapen H. Anat Rec (Hoboken). 2008 Jun; 291(6):714-20.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

[Optimization of hepatosplanchnic oxygenation in septic shock].
[Optimization of hepatosplanchnic oxygenation in septic shock].
Anasthesiol Intensivmed Notfallmed Schmerzther. 2008 Jan ;43(1):66-70; quiz 71.

PubMed
Impact of a specialized neurointensive care team on outcomes of critically ill a...
Impact of a specialized neurointensive care team on outcomes of critically ill acute ischemic stroke patients.
Neurocrit Care. 2008 ;9(3):287-92.

PubMed
Effect of dietary safflower phospholipid on plasma and liver lipids in rats fed ...
Effect of dietary safflower phospholipid on plasma and liver lipids in rats fed a hypercholesterolemic diet.
J Nutr Sci Vitaminol (Tokyo). 1991 Dec ;37(6):591-600.

PubMed
An improved relaxed complex scheme for receptor flexibility in computer-aided dr...
An improved relaxed complex scheme for receptor flexibility in computer-aided drug design.
J Comput Aided Mol Des. 2008 Sep ;22(9):693-705. Epub 2008 Jan 15 .

PubMed
Theanine, gamma-glutamylethylamide, a unique amino acid in tea leaves, modulates...
Theanine, gamma-glutamylethylamide, a unique amino acid in tea leaves, modulates neurotransmitter concentrations in the brain striatum interstitium in conscious rats.
Amino Acids. 2009 Jan ;36(1):21-7. Epub 2008 Jan 15 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: