Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Appl Prev Psychol. 2007 Dec;12(3):140-148.

Attentional window in schizophrenia and schizotypal personality: Insight from negative priming studies.

Author information

  • 1Department of Psychology, Vanderbilt University, 111, 21st Avenue South, Nashville, TN 37240, 615 322 3435.

Abstract

One of the core deficits that characterizes schizophrenia is an increase in distractibility and disinhibition at all levels of information processing. Patients with schizophrenia seem unable to focus attention on the relevant events while ignoring the irrelevant stimuli. This pattern of behavior is also observed in unmedicated schizotypal individuals who may carry liability for schizophrenia. In this review, we focus on studies of attentional inhibition, as assessed by the negative priming paradigm, to elucidate the relationships among deficits in inhibition, clinical symptoms and medication effects. We then consider models of the etiology of deficits in negative priming in schizophrenia and schizotypal personality. Finally, we discuss the potential power of utilizing hypothesis-driven cognitive paradigms in psychiatric research.

PMID:
18196180
[PubMed]
PMCID:
PMC2197156
Free PMC Article

Images from this publication.See all images (4)Free text

Figure 1
Figure 2
Figure 3
Figure 4
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk