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1: Presse Med. 2008 Jun;37(6 Pt 1):967-9. Epub 2008 Jan 11.Click here to read Links

[Bilateral papillary necrosis during indinavir treatment]

[Article in French]

Iba-Ba J, Yombi JC, Danse E, Van Beers B, Vandercam B.

Service de médecine interne A, Centre Hospitalier de Libreville, B.P. 2228, Libreville, Gabon. ibabajose@yahoo.fr

INTRODUCTION: Papillary necrosis results from ischemia of the renal medulla and papillae, induced by a variety of mechanisms. Papillary necrosis is a rare adverse effect of continuous protease-inhibitor therapy with indinavir. CASE: We describe the case of a patient who developed bilateral papillary necrosis. It was reversible after treatment interruption and increased hydration. CONCLUSION: This case shows the need to monitor kidney markers in patients under continuous treatment with indinavir.

PMID: 18191366 [PubMed - indexed for MEDLINE]

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  • Indinavir (Crixivan® )

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