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1: Clin Microbiol Infect. 2008 Apr;14(4):377-80. Epub 2008 Jan 11.Click here to read Links

Community-acquired methicillin-resistant Staphylococcus aureus infections: an emerging threat in Spain.

Manzur A, Dominguez AM, Pujol M, González MP, Limon E, Hornero A, Martín R, Gudiol F, Ariza J.

Infectious Diseases Service, Hospital Universitari de Bellvitge, L'Hospitalet Llobregat, Barcelona, Spain. admanzur@yahoo.com.ar

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has not been recognised previously as a cause of MRSA infections in Spain. Nineteen patients carrying Panton-Valentine leukocidin (PVL)-positive MRSA were identified in a Barcelona hospital, of whom 15 were immigrants, mostly from South America. Twelve developed skin and soft-tissue infections. The associated isolates carried the PVL gene and staphylococcal chromosomal cassette (SCC)mecIV. A dominant clone belonging to sequence type (ST)8 and related to the USA300 clone was identified by pulsed-field gel electrophoresis. This clone is emerging in Spain, primarily among immigrants from South America, but dissemination to the native Spanish population could increase.

PMID: 18190565 [PubMed - indexed for MEDLINE]