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J Biol Regul Homeost Agents. 2006 Jul-Dec;20(3-4):47-52.

Role of quercetin (a natural herbal compound) in allergy and inflammation.

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  • 1Department of Medicine, Section of Infectious Diseases, Boston University School of Medicine, Boston, MA, USA.

Abstract

An investigated flavonoid, quercetin, is reviewed in this article. Quercetin is a bioflavonoid found in red wine, grapefruit, onions, apples, black tea, and, in lesser amounts, in leafy green vegetables and beans. Quercetin has an antioxidant and anti-inflammatory activity and prevents cancer. Quercitin inhibits the growth of certain malignant cells in vitro, and histamine and most cyclin-dependent kinases and also displays unique anticancer properties. Quercetin is a natural compound that blocks substances involved in allergies and is able to act as an inhibitor of mast cell secretion, causes a decrease in the release of tryptase, MCP-1 and IL-6 and the down-regulation of histidine decarboxylase (HDC) mRNA from few mast cell lines. Quercetin is a safe, natural therapy that may be used as primary therapy or in conjunction with conventional methods.

PMID:
18187018
[PubMed - indexed for MEDLINE]
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