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Diabetes Care. 2008 Apr;31(4):805-7. doi: 10.2337/dc07-1117. Epub 2008 Jan 9.

Effect of lifestyle intervention on the occurrence of metabolic syndrome and its components in the Finnish Diabetes Prevention Study.

Author information

  • 1Diabetes Center, Finnish Diabetes Association, Tampere, Finland. pirjo.ilanneparikka@diabetes.fi

Abstract

OBJECTIVE:

The aim of this secondary analysis of the Finnish Diabetes Prevention Study was to assess the effects of lifestyle intervention on metabolic syndrome and its components.

RESEARCH DESIGN AND METHODS:

A total of 522 middle-aged overweight men and women with impaired glucose tolerance were randomized into an individualized lifestyle intervention group or a standard care control group. National Cholesterol Education Program criteria were used for the definition of metabolic syndrome.

RESULTS:

At the end of the study, with a mean follow-up of 3.9 years, we found a significant reduction in the prevalence of metabolic syndrome in the intervention group compared with the control group (odds ratio [OR] 0.62 [95% CI 0.40-0.95]) and in the prevalence of abdominal obesity (0.48 [0.28-0.81]).

CONCLUSIONS:

The results suggest that lifestyle intervention may also reduce risk of cardiovascular disease in the long run.

PMID:
18184907
[PubMed - indexed for MEDLINE]
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