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    Diabetes Care. 2008 Apr;31(4):726-7. Epub 2008 Jan 9.

    Tracking and prediction of arterial blood pressure from childhood to young adulthood in 868 patients with type 1 diabetes: a multicenter longitudinal survey in Germany and Austria.

    Knerr I, Dost A, Lepler R, Raile K, Schober E, Rascher W, Holl RW; Diabetes Data Acquisition System for Prospective Surveillance (DPV) Scientific Initiative Germany and Austria.

    Children's and Adolescents' Hospital, University of Erlangen-Nuremberg, D-91054 Erlangen, Germany. ina.knerr@uk-erlangen.de

    OBJECTIVE: Arterial blood pressure was followed in 868 patients with type 1 diabetes aged 6.0-19.9 years in 95 centers in Germany and Austria. RESEARCH DESIGN AND METHODS: European blood pressure reference data for 28,043 children and adolescents were used with respect to age and sex. Data were stratified into three groups: prepubertal, pubertal, and postpubertal. RESULTS: Up to 4% of the participants in the younger age-groups and 13.9% of the postpubertal patients exhibited blood pressure values >97th centile. Blood pressure levels correlated with A1C level and BMI Z score. Tracking of blood pressure revealed that children with elevated blood pressure had higher blood pressure in adolescence and young adulthood. CONCLUSIONS: Patients with higher blood pressure in childhood showed elevated blood pressure later in life. We need to focus on the diagnosis of hypertension in children with type 1 diabetes and to study the efficacy of early intervention.

    PMID: 18184906 [PubMed - indexed for MEDLINE]

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