Science. 1976 Sep 10;193(4257):1007-8.

Selective in vitro growth of T lymphocytes from normal human bone marrows.

Abstract

Selective growth of T lymphocytes occurred when unfractionated normal human bone marrow cells were cultured with conditioned medium obtained from phytohemagglutinin-stimulated normal human lymphocytes (Ly-CM). Cultures of up to 90 percent T cells have been maintained for more than 9 months. The T cells exhibited a strict growth dependence upon Ly-CM and were consistently negative for Epstein-Barr viral information.

PMID:: 181845; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, U.S. Gov't, P.H.S.

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Establishment of human cytotoxic T-cell lines specific for Epstein-Barr virus-transformed autologous cells. [Int J Cancer. 1981]
Establishment of human cytotoxic T-cell lines specific for Epstein-Barr virus-transformed autologous cells.
Sugamura K, Tanaka Y, Hinuma Y. Int J Cancer. 1981 Aug 15; 28(2):137-42.
Tumor growth inhibitory and natural suppressor activities of murine bone marrow cells: a comparative study. [Cell Immunol. 1997]
Tumor growth inhibitory and natural suppressor activities of murine bone marrow cells: a comparative study.
Seledtsov VI, Taraban VY, Seledtsova GV, Samarin DM, Avdeev IV, Senyukov VV, Kozlov VA. Cell Immunol. 1997 Nov 25; 182(1):12-9.
Derivation of cells with lytic activity against fresh and cultured tumors from human bone marrow. [J Surg Res. 1988]
Derivation of cells with lytic activity against fresh and cultured tumors from human bone marrow.
Jablons DM, Lotze MT. J Surg Res. 1988 Apr; 44(4):404-16.
IL-1 inhibits B cell differentiation in long term bone marrow cultures. [J Immunol. 1988]
IL-1 inhibits B cell differentiation in long term bone marrow cultures.
Dorshkind K. J Immunol. 1988 Jul 15; 141(2):531-8.
Interleukin-2 production and response to interleukin-2 by peripheral blood mononuclear cells from patients after bone marrow transplantation: II. Patients receiving soybean lectin-separated and T cell-depleted bone marrow. [Blood. 1987]
Interleukin-2 production and response to interleukin-2 by peripheral blood mononuclear cells from patients after bone marrow transplantation: II. Patients receiving soybean lectin-separated and T cell-depleted bone marrow.
Welte K, Keever CA, Levick J, Bonilla MA, Merluzzi VJ, Mertelsmann R, Evans R, O'Reilly RJ. Blood. 1987 Nov; 70(5):1595-603.

See reviews... See all...

Cited by over 100 PubMed Central articles

Scientific scholarship and impact factors. [Front Immunol. 2013]
Scientific scholarship and impact factors.
Smith KA. Front Immunol. 2013; 4:79. Epub 2013 Mar 28.
Toward a molecular understanding of adaptive immunity: a chronology, part I. [Front Immunol. 2012]
Toward a molecular understanding of adaptive immunity: a chronology, part I.
Smith KA. Front Immunol. 2012; 3:369. Epub 2012 Dec 6.
Therapeutic efficacy of Bifidobacterium longum-mediated human interleukin-2 with endostatin or TRAIL in transplanted tumors in mice. [Exp Ther Med. 2012]
Therapeutic efficacy of Bifidobacterium longum-mediated human interleukin-2 with endostatin or TRAIL in transplanted tumors in mice.
Yin Y, Kou L, Wang JJ, Xu GX. Exp Ther Med. 2012 Mar; 3(3):481-486. Epub 2011 Dec 19.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Selective in vitro growth of T lymphocytes from normal human bone marrows.
Selective in vitro growth of T lymphocytes from normal human bone marrows.
Science. 1976 Sep 10 ;193(4257):1007-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: