J Ethnopharmacol. 2008 Mar 5;116(2):377-80. Epub 2007 Dec 4.

Antimicrobial potential of Glycyrrhiza glabra roots.

Gupta VK, Fatima A, Faridi U, Negi AS, Shanker K, Kumar JK, Rahuja N, Luqman S, Sisodia BS, Saikia D, Darokar MP, Khanuja SP.

Source

Genetic Resources and Biotechnology Division, Central Institute of Medicinal and Aromatic Plants (CSIR), Kukrail Picnic Spot Road, P.O. CIMAP, Lucknow 226015, India.

Abstract

The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 microg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H(37)Ra and H(37)Rv strains at 29.16 microg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.

PMID:: 18182260; [PubMed - indexed for MEDLINE]

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