In this study, different modes of therapy for the removal of toxic chemicals from the human body have been assessed and compared. This consisted of: 1) thirteen inpatients in an environmentally controlled area in a hospital, 2) fourty-one outpatients with home environmental control and work area change, and 3) fifteen outpatients in a physical therapy/sauna program with a good environmental control. Attention to manipulation of food, food contaminants, water and air pollution as well as nutritional therapy was important in all groups. Each modality seemed efficacious in++ its own right; 100% inpatients, 80% sauna/physical therapy patients, and 70% outpatients improved their signs and symptoms. Inpatient therapy in a finally controlled environment was far superior to the other two modalities in clearing of symptoms, as well as in clearing of organic chemicals. Outpatient and sauna/physical therapy are efficacious for less ill patients.