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Am J Respir Crit Care Med. 2008 Mar 15;177(6):654-9. doi: 10.1164/rccm.200710-1610OC. Epub 2008 Jan 3.

Growth velocity predicts recurrence of sleep-disordered breathing 1 year after adenotonsillectomy.

Author information

  • 1Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA. raouf.amin@cchmc.org

Abstract

RATIONALE:

Adenotonsillectomy, the first line of treatment of sleep-disordered breathing (SDB), is the most commonly performed pediatric surgery. Predictors of the recurrence of SDB after adenotonsillectomy and its impact on cardiovascular risk factors have not been identified.

OBJECTIVES:

Demonstrate that gain velocity in body mass index (BMI) defined as unit increase in BMI/year confers an independent risk for the recurrence of SDB 1 year after adenotonsillectomy.

METHODS:

Children with SDB and hypertrophy of the tonsils and a comparison group of healthy children were followed prospectively for 1 year.

MEASUREMENTS AND MAIN RESULTS:

Serial polysomnographies, BMI, and blood pressure were obtained before adenotonsillectomy and 6 weeks, 6 months, and 1 year postoperatively. Gain velocity in BMI, BMI and being African American (odds ratios, 4-6/unit change/yr; 1.4/unit and 15, respectively) provided equal amounts of predictive power to the risk of recurrence of SDB. In the group that experienced recurrence, systolic blood pressure at 1 year was higher than at baseline and higher than in children who did not experience recurrence.

CONCLUSIONS:

Three clinical parameters confer independent increased risk for high recurrence of SDB after adenotonsillectomy: gain velocity in BMI, obesity, and being African American. A long-term follow-up of children with SDB and monitoring of gain velocity in BMI are essential to identifying children at risk for recurrence of SDB and in turn at risk for hypertension.

Comment in

PMID:
18174542
[PubMed - indexed for MEDLINE]
PMCID:
PMC2267339
Free PMC Article

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