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J Antimicrob Chemother. 2008 Mar;61(3):469-73. doi: 10.1093/jac/dkm499. Epub 2008 Jan 3.

Prolongation and quality of life for HIV-infected adults treated with highly active antiretroviral therapy (HAART): a balancing act.

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  • 1Immunodeficiency Clinic, University Health Network, University of Toronto, 200 Elizabeth Street, Toronto, Canada M5G 2C4.


Advances in highly active antiretroviral therapy (HAART) options for people living with HIV/AIDS have resulted in decreased morbidity and mortality. To some extent, the role of disease progression in eroding quality of life (QOL) erosion in the pre-HAART age is now supplanted by drug toxicities, one of the Achilles' heels of HAART. This article reviews research findings on treatment and QOL outcomes a decade into the HAART era.

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