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Bioinformatics. 2008 Feb 15;24(4):594-6. doi: 10.1093/bioinformatics/btm630. Epub 2008 Jan 2.

NetworkBLAST: comparative analysis of protein networks.

Author information

  • 1School of Computer Science, Tel Aviv University, Tel Aviv 69978, Israel. kalaevma@post.tau.ac.il

Abstract

The identification of protein complexes is a fundamental challenge in interpreting protein-protein interaction data. Cross-species analysis allows coping with the high levels of noise that are typical to these data. The NetworkBLAST web-server provides a platform for identifying protein complexes in protein-protein interaction networks. It can analyze a single network or two networks from different species. In the latter case, NetworkBLAST outputs a set of putative complexes that are evolutionarily conserved across the two networks.

AVAILABILITY:

NetworkBLAST is available as web-server at: www.cs.tau.ac.il/~roded/networkblast.htm.

PMID:
18174180
[PubMed - indexed for MEDLINE]
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