Cereb Cortex. 2008 Aug;18(8):1771-8. Epub 2007 Dec 28.

Dissociated pathways for successful memory retrieval from the human parietal cortex: anatomical and functional connectivity analyses.

Source

Department of Anatomy and Neurobiology, Center for Biomedical Imaging, Boston University School of Medicine, Boston, MA 02118, USA. emi@nmr.mgh.harvard.edu

Abstract

The parietal cortex has traditionally been implicated in spatial attention and eye-movement processes. Recent functional neuroimaging studies have found that activation in the parietal cortex is related to successful recognition memory. The activated regions consistently include the intraparietal sulcus in the lateral parietal cortex and the precuneus in the medial parietal cortex. However, little is known about the functional differences between lateral and medial parietal cortices in the memory retrieval process. In this study, we examined whether the human lateral and medial parietal lobes have differential anatomical and functional connectivity with the temporal lobe. To this end, we used functional magnetic resonance imaging to constrain the analysis of anatomical connectivity obtained by diffusion tensor imaging (DTI). Both DTI tractography and functional connectivity analysis showed that the lateral parietal region has anatomical and functional connections with the lateral temporal lobe, and the medial parietal region has connections with the medial temporal lobe. These results suggest the existence of segregated lateral and medial parieto-temporal pathways in successful memory retrieval.

PMID:: 18165283; [PubMed - indexed for MEDLINE]
PMCID:: PMC2790392

Free PMC Article

Images from this publication.See all images (2) Free text

Publication Types, MeSH Terms, Grant Support

Publication Types

MeSH Terms

Grant Support

NS44825/NS/NINDS NIH HHS/United States

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Memory - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Diffusion-weighted imaging tractography-based parcellation of the human parietal cortex and comparison with human and macaque resting-state functional connectivity. [J Neurosci. 2011]
Diffusion-weighted imaging tractography-based parcellation of the human parietal cortex and comparison with human and macaque resting-state functional connectivity.
Mars RB, Jbabdi S, Sallet J, O'Reilly JX, Croxson PL, Olivier E, Noonan MP, Bergmann C, Mitchell AS, Baxter MG, et al. J Neurosci. 2011 Mar 16; 31(11):4087-100.
Functional-anatomic correlates of memory retrieval that suggest nontraditional processing roles for multiple distinct regions within posterior parietal cortex. [J Neurosci. 2004]
Functional-anatomic correlates of memory retrieval that suggest nontraditional processing roles for multiple distinct regions within posterior parietal cortex.
Shannon BJ, Buckner RL. J Neurosci. 2004 Nov 10; 24(45):10084-92.
Episodic memory retrieval, parietal cortex, and the default mode network: functional and topographic analyses. [J Neurosci. 2011]
Episodic memory retrieval, parietal cortex, and the default mode network: functional and topographic analyses.
Sestieri C, Corbetta M, Romani GL, Shulman GL. J Neurosci. 2011 Mar 23; 31(12):4407-20.
Review Parietal lobe contributions to episodic memory retrieval. [Trends Cogn Sci. 2005]
Review Parietal lobe contributions to episodic memory retrieval.
Wagner AD, Shannon BJ, Kahn I, Buckner RL. Trends Cogn Sci. 2005 Sep; 9(9):445-53.
Review Top-down and bottom-up attention to memory: a hypothesis (AtoM) on the role of the posterior parietal cortex in memory retrieval. [Neuropsychologia. 2008]
Review Top-down and bottom-up attention to memory: a hypothesis (AtoM) on the role of the posterior parietal cortex in memory retrieval.
Ciaramelli E, Grady CL, Moscovitch M. Neuropsychologia. 2008; 46(7):1828-51. Epub 2008 Apr 8.

See reviews... See all...

Cited by 6 PubMed Central articles

Spatial and temporal dynamics of cortical networks engaged in memory encoding and retrieval. [Front Hum Neurosci. 2012]
Spatial and temporal dynamics of cortical networks engaged in memory encoding and retrieval.
Miller BT, D'Esposito M. Front Hum Neurosci. 2012; 6:109. Epub 2012 May 1.
Fiber density between rhinal cortex and activated ventrolateral prefrontal regions predicts episodic memory performance in humans. [Proc Natl Acad Sci U S A. 2011]
Fiber density between rhinal cortex and activated ventrolateral prefrontal regions predicts episodic memory performance in humans.
Schott BH, Niklas C, Kaufmann J, Bodammer NC, Machts J, Schütze H, Düzel E. Proc Natl Acad Sci U S A. 2011 Mar 29; 108(13):5408-13. Epub 2011 Mar 14.
Signatures of Memory: Brain Coactivations during Retrieval Distinguish Correct from Incorrect Recollection. [Front Behav Neurosci. 2010]
Signatures of Memory: Brain Coactivations during Retrieval Distinguish Correct from Incorrect Recollection.
Mendelsohn A, Furman O, Dudai Y. Front Behav Neurosci. 2010 Apr 19; 4:18. Epub 2010 Apr 19.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Dissociated pathways for successful memory retrieval from the human parietal cor...
Dissociated pathways for successful memory retrieval from the human parietal cortex: anatomical and functional connectivity analyses.
Cereb Cortex. 2008 Aug ;18(8):1771-8. Epub 2007 Dec 28 .

PubMed
Locked nucleic acids can enhance the analytical performance of quantitative meth...
Locked nucleic acids can enhance the analytical performance of quantitative methylation-specific polymerase chain reaction.
J Mol Diagn. 2008 Jan ;10(1):33-42. Epub 2007 Dec 28 .

PubMed
Leptin and ghrelin levels in patients with schizophrenia during different antips...
Leptin and ghrelin levels in patients with schizophrenia during different antipsychotics treatment: a review.
Schizophr Bull. 2008 Nov ;34(6):1189-99. Epub 2007 Dec 28 .

PubMed
Capsule acetylation does not impair recognition of serogroup C, W-135 and Y meni...
Capsule acetylation does not impair recognition of serogroup C, W-135 and Y meningococci by human dendritic cells.
Int J Med Microbiol. 2008 Oct ;298(7-8):591-7. Epub 2007 Dec 31 .

PubMed
Potassium currents contributing to action potential repolarization in dissociate...
Potassium currents contributing to action potential repolarization in dissociated cultured rat superior cervical sympathetic neurones.
Neurosci Lett. 1991 Dec 9 ;133(2):298-302.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: