Display Settings:

Format

Send to:

Choose Destination
    Cells Tissues Organs. 2008;187(1):6-12. Epub 2007 Dec 11.

    Molecular determinants of bat wing development.

    Source

    Howard Hughes Medical Institute, Pediatrics Department, University of Colorado at Denver, Denver, USA. kesears@alumni.uchicago.edu

    Abstract

    The specialization of the forelimb into a wing allowed bats to become the only mammals to achieve powered flight. Recent studies in developmental biology have begun to elucidate the molecular mechanisms behind elements of this important morphological transformation. Specifically, researchers have identified molecular changes contributing to: the formation of the bat wing membrane, the elongation of skeletal elements of the bat wing and the reduction of the bat ulna. The general picture emerging from this research is that small changes in the expression of genes critical to many aspects of development have driven large changes in bat wing morphology. Thus, bats can be added to the growing list of groups in which expression changes in key developmental genes have been linked to the evolution of morphological innovations (e.g. early bilaterians, cetaceans, insects).

    (c) 2007 S. Karger AG, Basel

    PMID:
    18160799
    [PubMed - indexed for MEDLINE]

      Supplemental Content

      Icon for S. Karger AG, Basel, Switzerland

      Save items

      loading

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      Write to the Help Desk