Abstract
Based on experimentally determined concentrations of PCr, Pi, ATP, and H+, the ADP and AMP concentrations and the free energy for the ATP hydrolysis in normal human brain and muscle were calculated assuming that the creatine kinase- and the myokinase-catalyzed reactions were in equilibrium, accounting for changes in pH and free Mg2+ ion concentration.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adenosine Diphosphate / analysis*
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Adenosine Monophosphate / analysis*
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Adenosine Triphosphate / metabolism*
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Brain / metabolism*
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Cytosol / metabolism
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Energy Metabolism
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Humans
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Hydrolysis
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Magnetic Resonance Spectroscopy*
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Muscles / metabolism*
Substances
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Adenosine Monophosphate
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Adenosine Diphosphate
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Adenosine Triphosphate