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Ann N Y Acad Sci. 2008 Mar;1125:267-79. Epub 2007 Dec 20.

Cellulases of mesophilic microorganisms: cellulosome and noncellulosome producers.

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  • 1Section of Molecular and Cellular Biology, University of California, One Shields Avenue, Davis, CA 95616, USA.


The cellulolytic activity of mesophilic bacteria and fungi is described, with special emphasis on the large extracellular enzyme complex called the cellulosome. The cellulosome is composed of a scaffolding protein, which is attached to various cellulolytic and hemicellulolytic enzymes, and this complex allows the organisms to degrade plant cell walls very efficently. The enzymes include a variety of cellulases, hemicellulases, and pectinases that work synergistically to degrade complex cell-wall molecules.

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