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1: Chem Biol. 2007 Dec;14(12):1309-11.Click here to read Links
Comment on:
Chem Biol. 2007 Dec;14(12):1347-56.

2-AG + 2 new players = forecast for therapeutic advances.

Marrs W, Stella N.

Graduate Program in Neurobiology and Behavior, University of Washington, Seattle, WA 98195, USA.

In this issue of Chemistry & Biology, Blankman et al. identify new enzymes hydrolyzing the endocannabionoid 2-arachidonoyl glycerol (2-AG), increasing the complexity of endocannabinoid signaling in the brain, but also pinpointing additional therapeutic targets.

PMID: 18096497 [PubMed - indexed for MEDLINE]