2-AG + 2 new players = forecast for therapeutic ad... [Chem Biol. 2007] - PubMed

A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. [Chem Biol. 2007]
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol.
Blankman JL, Simon GM, Cravatt BF. Chem Biol. 2007 Dec; 14(12):1347-56.
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus. [Nat Neurosci. 2005]
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus.
Makara JK, Mor M, Fegley D, Szabó SI, Kathuria S, Astarita G, Duranti A, Tontini A, Tarzia G, Rivara S, et al. Nat Neurosci. 2005 Sep; 8(9):1139-41. Epub 2005 Aug 7.
Fatty pain cures. [Chem Biol. 2007]
Fatty pain cures.
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Review Monoglyceride lipase as an enzyme hydrolyzing 2-arachidonoylglycerol. [Chem Biodivers. 2007]
Review Monoglyceride lipase as an enzyme hydrolyzing 2-arachidonoylglycerol.
Saario SM, Laitinen JT. Chem Biodivers. 2007 Aug; 4(8):1903-13.
Review Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol. [Biofactors. 2011]
Review Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol.
Ueda N, Tsuboi K, Uyama T, Ohnishi T. Biofactors. 2011 Jan; 37(1):1-7. Epub 2010 Nov 29.

Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism. [Am J Hum Genet. 2010]
Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism.
Fiskerstrand T, H'mida-Ben Brahim D, Johansson S, M'zahem A, Haukanes BI, Drouot N, Zimmermann J, Cole AJ, Vedeler C, Bredrup C, et al. Am J Hum Genet. 2010 Sep 10; 87(3):410-7.
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. [Nat Neurosci. 2010]
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.
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