Source
Divisão de Neurologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Rua Vicente Oropallo 612, São Paulo, SP, Brazil. sermaju@uol.com.br
Abstract
Mesial temporal sclerosis is the most frequent cause of drug-resistant temporal lobe epilepsy but has a satisfactory response to surgery, and is considered infrequent in children.
OBJECTIVE:
To evaluate the clinical, electrographic and radiological spectrum of the disease in children.
METHOD:
Retrospective study by review of charts of 44 children with a diagnosis of mesial temporal sclerosis on magnetic resonance imaging, attended at the "Hospital das Clínicas" of the University of São Paulo Faculty of Medicine.
RESULTS:
Febrile seizure was identified in the history of 54% of the patients. Injuries at the left side predominated in patients with schooling difficulties (p=0.049), in those with first seizures between six months and five years (p=0.021) and in those with complex febrile seizure (p=0.032). Thirteen patients were submitted to surgery and of these, eight remained without seizures.
CONCLUSION:
Febrile seizure may be related in a more direct way to the presence of left-side mesial temporal sclerosis.