AIDS. 2007 Nov 12;21(17):2347-9.

Do CD8(+)CD25(+) cells predict immune reconstitution syndrome in HIV-positive patients who begin HAART?

Cianchetta-Sívori M, Raso S, Fernández-Guerrero M, Górgolas M, García R.

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Department of Immunology, Fundación Jimenez Díaz-Capio, Madrid, Spain.

Abstract

Although undesirable, immune reconstitution syndrome (IRS) indicates a favourable effect of HAART and it should be differentiated from an opportunistic infection because of their distinct implications and management. Our group analysed different immunological parameters with the aim of identifying IRS predictors in patients who begin HAART. We found that CD8(+)CD25(+) cell pretreatment values in patients who developed IRS were four times higher than in those patients who did not develop IRS.

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AIDS. 2008 Apr 23;22(7):911.

PMID:: 18090286; [PubMed - indexed for MEDLINE]

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