Crit Care. 2007;11(6):180.

Positive end-expiratory pressure in acute respiratory distress syndrome: should the 'open lung strategy' be replaced by a 'protective lung strategy'?

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Réanimation Chirurgicale Polyvalente Pierre Viars, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Université Pierre et Marie Curie of Paris - 6, 47/83 boulevard de l'Hôpital, Paris Cédex 13, France. jjrouby.pitie@invivo.edu

Abstract

In patients with acute respiratory distress syndrome, positive end-expiratory pressure is associated with alveolar recruitment and lung hyperinflation despite the administration of a low tidal volume. The best positive end-expiratory pressure should correspond to the best compromise between recruitment and distension, a condition that coincides with the best respiratory elastance.

Comment in

Crit Care. 2008;12(1):408; author reply 408.

Comment on

Crit Care. 2007;11(4):R86.

PMID:: 18086329; [PubMed - indexed for MEDLINE]
PMCID:: PMC2246215

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Cited by 1 PubMed Central article

The quest for optimal positive end-expiratory pressure continues. [Crit Care. 2008]
The quest for optimal positive end-expiratory pressure continues.
Markhorst D, Kneyber M, van Heerde M. Crit Care. 2008; 12(1):408; author reply 408.

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