A shared vision. [Dev Cell. 2007]

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1: Dev Cell. 2007 Dec;13(6):769-71. Links

A shared vision.

Hogan B.

Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA. b.hogan@cellbio.duke.edu

One of today's most powerful technologies in biomedical research--the creation of mutant mice by gene targeting in embryonic stem (ES) cells--was finally celebrated in this year's Nobel Prize in Medicine. The history of how ES cells were first discovered and genetically manipulated highlights the importance of collaboration among scientists from different backgrounds with a shared vision.

Personal Name as Subject:: Capecchi M; Evans M; Smithies O

PMID: 18061560 [PubMed - indexed for MEDLINE]

[Three scientists awarded with Nobel Prize for gene modification technique] [Lakartidningen. 2007]
Knock out, knock in, knock down--genetically manipulated mice and the Nobel Prize. [N Engl J Med. 2007]
[The Nobel Prize in Physiology or Medicine 2007 for the development of 'knockout' technology] [Ned Tijdschr Geneeskd. 2007]
ReviewGenome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology. [An Acad Bras Cienc. 2001]
ReviewKnockout mouse models in pain research. [Methods Mol Med. 2004]

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A shared vision.

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