Science. 1976 Jul 2;193(4247):58-9.

Ethanol-induced depletion of cerebellar guanosine 3',5' -cyclic monophosphate.

Abstract

Single doses of ethanol a severe depletion (95 percent) of cerebellar guanosine 3',5' -cyclic monophosphate (cyclic GMP) within 1 hour after administration. The degree of this depletion is dose-dependent and is a function of the amount of ethanol in the blood. Interactions between ethanol and cyclic GMP may account for some of the intoxicating properties of ethanol.

PMID:: 180596; [PubMed - indexed for MEDLINE]

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Lithium antagonism of ethanol-induced depletion of cerebellar guanosine-3',5'-cyclic monophosphate and stimulation of striatal dopamine release. [J Stud Alcohol. 1979]
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Cited by 1 PubMed Central article

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