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Pediatr Blood Cancer. 2008 Mar;50(3):692-4.

World disparities in risk definition and management of retinoblastoma: a report from the International Retinoblastoma Staging Working Group.

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  • 1Hospital JP Garrahan, Buenos Aires, Argentina and International Outreach Program, St Jude Children's Research Hospital, Memphis, Tennessee, USA. guillermo.chantada@stjude.org


Following from the publication of the International Retinoblastoma Staging System, an open internet discussion group was created at the www.cure4kids.org resource. The results of a survey distributed among participants are discussed. Although most patients with retinoblastoma were treated under prospective protocols, there was a wide variation in the definition of risk criteria and in the criteria for giving adjuvant chemotherapy following enucleation. Definition of high-risk histological features and the criteria for use of adjuvant therapy will be standardized in future studies. Internet meetings are a valuable mechanism for enabling participation from under-resourced countries in the development of cooperative studies.

(c) 2007 Wiley-Liss, Inc.

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