We report 2 male patients who had bilateral cataract surgery. Both patients had features of the intraoperative floppy-iris syndrome (IFIS) in both eyes, and both were taking oral finasteride for the management of benign prostatic hyperplasia (BPH). We conclude that finasteride can be associated with IFIS, so it is important to take detailed medical histories of patients having cataract surgery, paying attention to a history of BPH and its treatment.