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Eur Urol. 2008 Apr;53(4):845-8. Epub 2007 Nov 20.

Neoadjuvant sutent induction therapy may effectively down-stage renal cell carcinoma atrial thrombi.

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  • 1Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, QC, Canada. <>


A 75-yr-old previously healthy woman presented with gross hematuria, European Cooperative Oncology Group 0, and an 11-cm renal mass with right atrial thrombus. The patient refused the sternotomy. She was offered two cycles of sunitinib maleate (Sutent) induction therapy to down-stage the thrombus and to reduce the extent of the surgery.

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