J Proteome Res. 2008 Jan;7(1):40-4. Epub 2007 Dec 4.

Posterior error probabilities and false discovery rates: two sides of the same coin.

Käll L, Storey JD, MacCoss MJ, Noble WS.

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Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.

Abstract

A variety of methods have been described in the literature for assigning statistical significance to peptides identified via tandem mass spectrometry. Here, we explain how two types of scores, the q-value and the posterior error probability, are related and complementary to one another.

PMID:: 18052118; [PubMed - indexed for MEDLINE]

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