[Efficiency of preemptive intravenous paracetamol analgesia in abdominal surgery]

Anesteziol Reanimatol. 2007 Sep-Oct:(5):38-40.
[Article in Russian]

Abstract

In a randomized, controlled study, 50 patients underwent elective surgery for abdominal cancer lesions under perioperative epidural analgesia. All the patients were randomized to receive paracetamol in a single intravenous dose of 1 g or placebo 30 minutes prior to the start of surgery. The use of 1 g of paracetamol as a single intravenous preemptive dose in abdominal surgery with perioperative epidural analgesia does not reduce the consumption of the analgesic and the intensity of pain in the postoperative period.

Publication types

  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Acetaminophen / administration & dosage
  • Acetaminophen / therapeutic use*
  • Analgesia, Epidural / methods
  • Analgesics, Non-Narcotic / administration & dosage
  • Analgesics, Non-Narcotic / therapeutic use*
  • Colonic Neoplasms / surgery
  • Digestive System Surgical Procedures / methods*
  • Female
  • Humans
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Pain Measurement
  • Pain, Postoperative / prevention & control*
  • Preoperative Care / methods*
  • Stomach Neoplasms / surgery
  • Time Factors

Substances

  • Analgesics, Non-Narcotic
  • Acetaminophen