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Genome Biol. 2007;8 Suppl 1:S9.

Insertional mutagenesis strategies in zebrafish.

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  • 1Institute of Genomics and Integrative Biology, Council for Scientific and Industrial Research, Mall Road, Delhi 110007, India.

Abstract

We review here some recent developments in the field of insertional mutagenesis in zebrafish. We highlight the advantages and limitations of the rich body of retroviral methodologies, and we focus on the mechanisms and concepts of new transposon-based mutagenesis approaches under development, including prospects for conditional 'gene trapping' and 'gene breaking' approaches.

PMID:
18047701
[PubMed - indexed for MEDLINE]
PMCID:
PMC2106850
Free PMC Article

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