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Genome Biol. 2007;8 Suppl 1:S8.

Transposons as tools for enhancer trap screens in vertebrates.

Author information

  • 1Institute of Molecular and Cell Biology, Biopolis Dr, Proteos, 138673, Singapore. vlad@imcb.a-star.edu.sg

Abstract

DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the medaka fish derived Tol2, to enhancer trapping in zebrafish, and how this approach compares with others that have a similar objective.

PMID:
18047700
[PubMed - indexed for MEDLINE]
PMCID:
PMC2106835
Free PMC Article
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