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    J Appl Microbiol. 2007 Dec;103(6):2258-66.

    Characterization of the cellulolytic and hydrogen-producing activities of six mesophilic Clostridium species.

    Source

    Department of Civil and Environmental Engineering, The Pennsylvania State University, University Park, PA 16802, USA.

    Abstract

    AIMS:

    To characterize cellulolytic, hydrogen-producing clostridia on a comparable basis.

    METHODS AND RESULTS:

    H(2) production from cellulose by six mesophilic clostridia was characterized in standardized batch experiments using MN301 cellulose, Avicel and cellobiose. Daily H(2) production, substrate degradation, biomass production and the end-point distribution of soluble fermentation products varied with species and substrates. All species produced a significant amount of H(2) from cellobiose, with Clostridium acetobutylicum achieving the highest H(2) yield of 2.3 mol H(2) mol(-1) hexose, but it did not degrade cellulose. Clostridium cellulolyticum and Clostridium populeti catalysed the highest H(2) production from cellulose, with yields of 1.7 and 1.6 mol H(2 )mol(-1) hexose from MN301 and 1.6 and 1.4 mol H(2) mol(-1) hexose from Avicel, respectively. These species also achieved 25-100% higher H(2) production rates from cellulose than the other species.

    CONCLUSIONS:

    These cellulolytic, hydrogen-producing clostridia varied in H(2) production, with Cl. cellulolyticum and Cl. populeti achieving the highest H(2) yields and cellulose degradation.

    SIGNIFICANCE AND IMPACT OF THE STUDY:

    The fermentation of cellulosic materials presents a means of H(2) production from renewable resources. This standardized comparison provides a quantitative baseline for improving H(2) production from cellulose through medium and process optimization and metabolic engineering.

    PMID:
    18045409
    [PubMed - indexed for MEDLINE]

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