Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Curr Opin Immunol. 2007 Dec;19(6):623-32. Epub 2007 Nov 26.

Microarray-based identification of novel biomarkers in IL-1-mediated diseases.

Author information

  • 1Baylor Institute for Immunology Research and Baylor Research Institute, Dallas, TX, USA.

Abstract

Interleukin 1b (IL-1b) is emerging as mediator of a wide range of human diseases. Availability of IL-1 blockers that result in clinical benefits to patients with these diseases is creating a demand for biomarkers to diagnose as well as to predict and follow responses to therapy. Blood gene expression profiling can be used to identify such biomarkers. This review will summarize recent studies in the field and will discuss some of the challenges raised by the use of this technology in biomarker discovery.

PMID:
18036805
[PubMed - indexed for MEDLINE]
PMCID:
PMC2747489
Free PMC Article

Images from this publication.See all images (3)Free text

Figure 1
Figure 2
Figure 3
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk