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Nat Rev Cancer. 2007 Dec;7(12):949-60.

Innovations in image-guided radiotherapy.

Author information

  • 1UZ Brussel, Oncologisch Centrum, Radiotherapie, Laarbeeklaan 101, B-1090 Brussels, Belgium. dirk.verellen@uzbrussel.be

Erratum in

  • Nat Rev Cancer. 2008 Jan;8(1):71.

Abstract

The limited ability to control for the location of a tumour compromises the accuracy with which radiation can be delivered to tumour-bearing tissue. The resultant requirement for larger treatment volumes to accommodate target uncertainty restricts the radiation dose because more surrounding normal tissue is exposed. With image-guided radiotherapy (IGRT) these volumes can be optimized and tumoricidal doses can be delivered, achieving maximal tumour control with minimal complications. Moreover, with the ability of high-precision dose delivery and real-time knowledge of the target volume location, IGRT has initiated the exploration of new indications for radiotherapy, some of which were previously considered infeasible.

PMID:
18034185
[PubMed - indexed for MEDLINE]
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