The Milwaukee Hoimicide Review Commission (MHRC) is a multi-level, multi-disciplinary, and multiagency homicide review process aimed at reducing the occurrence of homicides in Milwaukee. Based on the public health approach to violence reduction, the MHRC has 3 goals: (1) to gain a better understanding of homicide through strategic problem analysis, (2) to develop innovative, effective responses, and (3) to focus limited enforcement and intervention activities on identifiable risks. The MHIRC creates an environment for many disciplines and agencies to share information and work collectively on violence prevention strategies. Since its inception, the MHRC has reviewed over 150 homicides and developed over 100 recommendations aimed at reducing homicide. These recommendations are based on themes that emerge from case reviews and focus on initiating change at system, agency/organization, and individual levels. The MHRC has many accomplishments to date, including improved communication between local, state, and federal criminal justice agencies; assistance in immediate investigations new strategic criminal justice activities; changes in ineffective agency practices; and new cooperative efforts between community service providers. Future plans include the continuation and expansion of initiatives including greater community impact and developinga Center of Excellence in community and public safety serving Milwaukee and the state of Wisconsin.