Synthesis and some reactions of 3-chloro-2-(cyanomethylene)-1,2-dihydroquinoxalines

Craig A Obafemi; Wolfgang Pfleiderer

doi:10.3390/90400223

Synthesis and some reactions of 3-chloro-2-(cyanomethylene)-1,2-dihydroquinoxalines

Molecules. 2004 Mar 31;9(4):223-31. doi: 10.3390/90400223.

Authors

Craig A Obafemi¹, Wolfgang Pfleiderer

Affiliation

¹ Department of Chemistry, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria. craigoba@oauife.edu.ng

Abstract

2,3-Dichloroquinoxaline and some of its derivatives have been reacted with malononitrile and ethyl cyanoacetate to yield a variety of 3-chloro-2-(cyanomethylene)- 1,2-dihydroquinoxaline derivatives. The reaction of 3-chloro-2-(dicyanomethylene)-1,2- dihydroquinoxaline (2e) with pyridine and its methyl derivatives led to the zwitterionic structures 6a-6c. The structures of the newly synthesized compounds were assigned by spectroscopic data and elemental analyses.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chlorine Compounds* / chemical synthesis
Chlorine Compounds* / chemistry
Molecular Structure
Pyridines / chemistry
Quinoxalines* / chemical synthesis
Quinoxalines* / chemistry

Substances

Chlorine Compounds
Pyridines
Quinoxalines