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Nucleic Acids Res. 2008 Jan;36(Database issue):D102-6. Epub 2007 Nov 15.

JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update.

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  • 1Computational Biology Unit, Bergen Center for Computational Science, University of Bergen, Thormøhlensgate 55, N-5008 Bergen, Norway.

Abstract

JASPAR is a popular open-access database for matrix models describing DNA-binding preferences for transcription factors and other DNA patterns. With its third major release, JASPAR has been expanded and equipped with additional functions aimed at both casual and power users. The heart of the JASPAR database-the JASPAR CORE sub-database-has increased by 12% in size, and three new specialized sub-databases have been added. New functions include clustering of matrix models by similarity, generation of random matrices by sampling from selected sets of existing models and a language-independent Web Service applications programming interface for matrix retrieval. JASPAR is available at http://jaspar.genereg.net.

PMID:
18006571
[PubMed - indexed for MEDLINE]
PMCID:
PMC2238834
Free PMC Article
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