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Clin Genet. 2008 Jan;73(1):14-23. Epub 2007 Nov 13.

Sex-linked deafness.

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  • 1Department of Genetics, Institute of Child Health, Athens, Greece.


Many human syndromes associated with hearing loss are caused by disease genes located on the X chromosome, but few X-linked loci for non-syndromic hearing loss have been reported. Surprisingly, a Y-linked locus has been identified, representing one of the only disease loci on the Y chromosome. This study reviews the different sex-linked genes and loci on the X- and Y chromosome leading to syndromic and especially non-syndromic hearing loss.

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