Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Curr Infect Dis Rep. 2007 Nov;9(6):485-500.

Bacterial vaginosis: culture- and PCR-based characterizations of a complex polymicrobial disease's pathobiology.

Author information

  • 1Division of Infectious Diseases, Harper University Hospital, 3990 John R, Detroit, MI 48201, USA.

Abstract

Bacterial vaginosis (BV) is an enigmatic polymicrobial disease, and its evolution and pathobiology will not be solved by traditional culture-based methods. Characterization of the vaginal microbiota by polymerase chain reaction-based methods holds great promise. Molecular studies have identified species not detected by culture, but they also have missed some species identified by culture. These studies allow classification of both normal and BV patients based on distinct microbiologic profiles, which may prove important in accessing risk of BV, response to treatment, and risk of complications. More studies using new generations of primers and standardized methods are needed, and data must be analyzed after grouping patients according to microbiologic profiles.

PMID:
17999885
[PubMed]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk